Molecularly Targeted Therapy: Past, Present and Future
نویسندگان
چکیده
منابع مشابه
Mizaj past, present and future
Temperament (Mizaj), as an individual factor, has great importance in traditional medicine and its use in diagnosis and treatment of diseases, as well as the individual lifestyle is very common. Since medicine moves toward Personalized Medicine, the root of individual differences will find its position in different aspects of medicine in early future. In traditional medicine, temperament is ...
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Background Tuberculosis (TB) is the second-most common cause of death from infectious disease (after those due to HIV/AIDS). Roughly one-third of the world's population has been infected with M. tuberculosis, with new infections occurring in about 1% of the population each year. People with active TB can infect 10-15 other people through close contact over the course of a year. Materials and ...
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The IGF-I receptor (IGF-IR) has been studied as an anti-cancer target. However, monotherapy trials with IGF-IR targeted antibodies or with IGF-IR specific tyrosine kinase inhibitors have, overall, been very disappointing in the clinical setting. This review discusses potential reasons why IGF-I R targeted therapy fails to inhibit growth of human cancers. It has become clear that intracellular s...
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Medullary thyroid carcinoma occurs most often as a sporadic malignancy, although in approximately 30% of cases, it occurs as part of the multiple endocrine neoplasia type 2 (MEN2) syndromes MEN2A and MEN2B or the related disease, familial medullary thyroid carcinoma. These three syndromes, inherited as autosomal dominant traits, are clinically characterized by near complete penetrance but varia...
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ژورنال
عنوان ژورنال: Chemotherapy: Open Access
سال: 2012
ISSN: 2167-7700
DOI: 10.4172/2167-7700.1000105